Amigatin LS 100/10mg Tablet 10s
Amigatin LS 100mg/10mg Tablet is a combination medicine used for the treatment of neuropathic pain. It works by increasing the level of chemical messengers in the brain. This helps in regulating the mood and stopping the movement of pain signals from nerves to the brain. Amigatin LS 100mg/10mg Tablet is taken by mouth with or without food, preferably at bedtime. It is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of the treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor as it may increase the seizure frequency and can be life-threatening in some cases. Avoid taking antacids with this medicine as antacids make it harder for your body to absorb this medicine. Some common side effects of this medicine are constipation, difficulty in urination, weight gain, and dryness in mouth. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain and to control it, you should exercise regularly and take a balanced diet. Before taking this medicine let your doctor know if you suffer from kidney or liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Written by: Syed Jommy Abbas, B. Pharma
Reviewed by: Dr. Devika Rani, MBBS
Last updated on: 24-06-2025
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More About Amigatin LS 100/10mg Tablet 10s
Quick Summary
Amigatin LS 100mg/10mg Tablet is a combination medicine used for the treatment of neuropathic pain. It works by increasing the level of chemical messengers in the brain. This helps in regulating the mood and stopping the movement of pain signals from nerves to the brain. Amigatin LS 100mg/10mg Tablet is taken by mouth with or without food, preferably at bedtime. It is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of the treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor as it may increase the seizure frequency and can be life-threatening in some cases. Avoid taking antacids with this medicine as antacids make it harder for your body to absorb this medicine. Some common side effects of this medicine are constipation, difficulty in urination, weight gain, and dryness in mouth. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain and to control it, you should exercise regularly and take a balanced diet. Before taking this medicine let your doctor know if you suffer from kidney or liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Benefits of Amigatin LS 100/10mg Tablet 10s
Neuropathic pain
In Neuropathic pain Amigatin LS 100mg/10mg Tablet is a combination of medicines used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles, or spinal cord injury. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. It is thought to work by interfering with pain signals that travel through the damaged nerves and the brain. Amigatin LS 100mg/10mg Tablet regularly will improve your physical and social functioning and overall quality of life. It takes a few weeks to work so you need to take it regularly even if you feel it is not doing any good. Once your symptoms have gone you should still keep taking the medicine until your doctor advises you to stop.
Side Effects of Amigatin LS 100/10mg Tablet 10s
The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you're worried about them. ['Difficulty in urination, Weight gain, Sleepiness, Dizziness, Tiredness, Uncoordinated body movements, Increased heart rate, Orthostatic hypotension (sudden lowering of blood pressure on standing), Blurred vision, Dryness in mouth']
Directions for Use
Follow your doctor's guidance regarding the dose and duration of this medication. Ingest it without breaking or crushing. Do not chew, crush or break it. Amigatin LS 100mg/10mg Tablet can be taken it with or without food, although it's advisable to take it consistently at the same time.
How it works
Amigatin LS 100mg/10mg Tablet is a combination of two medicines: Gabapentin and Amitriptyline. Gabapentin is an alpha 2 delta ligand which decreases the pain by modulating calcium channel activity of the nerve cells. Amitriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Together, they relieve neuropathic pain (pain from damaged nerves).
Alcohol
Unsafe: Avoid consuming alcohol with Amigatin LS 100mg/10mg Tablet as it is deemed unsafe.
Pregnancy
Seek medical advice from your doctor: Amigatin LS 100mg/10mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Doctor consultation is advised.
Breast feeding
Seek medical advice from your doctor: Amigatin LS 100mg/10mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
Not Safe: Amigatin LS 100mg/10mg Tablet may cause side effects which could affect your ability to drive. Amigatin LS 100mg/10mg Tablet may impair your alertness which may affect your ability to drive.
Kidney
Safe when prescribed by an expert: Amigatin LS 100mg/10mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Amigatin LS 100mg/10mg Tablet may not be needed in these patients. Doctor consultation is advised.
Liver
Caution Advised: Amigatin LS 100mg/10mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Amigatin LS 100mg/10mg Tablet may be needed. Doctor consultation is advised. Use of Amigatin LS 100mg/10mg Tablet is not recommended in patients with severe liver disease.
What If You Forget to take Amigatin LS 100/10mg Tablet 10s?
If a dose of Amigatin LS 100mg/10mg Tablet is missed, take it promptly. However, if your next dose is approaching, skip the missed dose and resume your regular schedule. Avoid doubling the dose.
Storage Advice
Store in a cool and dry place, and keep the temperature below 30�C
Quick Tips for Amigatin LS 100/10mg Tablet 10s
Amigatin LS 100mg/10mg Tablet is used to treat certain types of long-lasting pain caused by damage to nerves. Inform your doctor if you are taking any other pain-relieving medicines. Along with taking this medicine, your doctor might advise you to undergo physiotherapy to get relief from pain. Avoid taking antacids 2 hours before or after taking Amigatin LS 100mg/10mg Tablet as they make it harder for your body to absorb the medicine.
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SCO-58, 59, Sector-17D Chandigarh-160017
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