Premarin Vaginal Cream is a female sex hormone (estrogen). It is a part of female hormone replacement therapy which helps in treating estrogen deficiency symptoms like hot flushes (red and warm face) and vaginal dryness.In some cases, Premarin Vaginal Cream is also used to treat breast cancer and prostate cancer along with other anticancer medicines. It is to be taken at a fixed time(s) daily. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed a dose, take it as soon as you remember it. Do not skip any dose and finish the full course of treatment. The treatment should not be stopped abruptly without consulting your doctor as this may affect the potency of this medicine.The most common side effects of this HRT are headaches, breast pain, irregular vaginal bleeding or spotting, abdominal cramps or bloating, and vomiting. Some of the warning signs and symptoms that need immediate medical attention are breast lumps, unusual vaginal bleeding, dizziness and faintness, severe headaches, chest pain, shortness of breath, pains in your legs, etc.Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Before you initiate with this HRT, you must consult the doctor if you have a history of unexplained vaginal bleeding or if you have ever had a blood clot in your legs or your lungs. If you are pregnant or breastfeeding, you should tell your doctor before taking this medicine. Your doctor may suggest you some diagnostic or laboratory tests to know the effects and side effects of this medicine on your body.
Last updated on: 30-04-2025
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Premarin Vaginal Cream is a female sex hormone (estrogen). It is a part of female hormone replacement therapy which helps in treating estrogen deficiency symptoms like hot flushes (red and warm face) and vaginal dryness.In some cases, Premarin Vaginal Cream is also used to treat breast cancer and prostate cancer along with other anticancer medicines. It is to be taken at a fixed time(s) daily. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed a dose, take it as soon as you remember it. Do not skip any dose and finish the full course of treatment. The treatment should not be stopped abruptly without consulting your doctor as this may affect the potency of this medicine.The most common side effects of this HRT are headaches, breast pain, irregular vaginal bleeding or spotting, abdominal cramps or bloating, and vomiting. Some of the warning signs and symptoms that need immediate medical attention are breast lumps, unusual vaginal bleeding, dizziness and faintness, severe headaches, chest pain, shortness of breath, pains in your legs, etc.Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Before you initiate with this HRT, you must consult the doctor if you have a history of unexplained vaginal bleeding or if you have ever had a blood clot in your legs or your lungs. If you are pregnant or breastfeeding, you should tell your doctor before taking this medicine. Your doctor may suggest you some diagnostic or laboratory tests to know the effects and side effects of this medicine on your body.
Hormone replacement therapy
In Hormone replacement therapy : Hormone placement therapy (HRT) is a treatment to relieve symptoms of menopause such as hot flushes, vaginal dryness, and reduced sex drive. Since menopause can last for several years, this treatment can make a big improvement to your daily life and mood. Estrogen is one of two important hormones (the other is progesterone) used in this treatment. Vaginal tablets and gels are an easy way to deliver hormones but may not treat all the symptoms. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.
Side effects of Premarin Vaginal Cream The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you're worried about them Common side effects of Premarin Abnormal vaginal bleeding Irritation Pelvic pain Breast pain Irregular vaginal bleeding Edema (swelling)Vaginal spotting Vaginal itching Depression Leg cramps Abdominal cramp Vaginal burning sensation
How to use Premarin Vaginal Cream This medication is designated for external application solely. Utilize it according to the dosage and duration instructed by your doctor. Check the label for directions before use. Ensure that the affected area is clean and dry and apply the cream by using applicator. Wash your hands after applying.
How Premarin Vaginal Cream works Premarin Vaginal Cream is a mixture of estrogens (a female sex hormone). As a part of the hormone replacement therapy, it works by maintaining the estrogen levels in the body in menopausal women. It also prevents the vaginal wall from becoming thin and dry thereby reducing inflammation.
Alcohol
No interaction has been found or established.
Pregnancy
Premarin Vaginal Cream is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Doctor consultation is advised.
Breast feeding
Premarin Vaginal Cream is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
No interaction found/established
Kidney
No interaction found/established
Liver
No interaction found/established
If a dose of Premarin Vaginal Cream is missed, take it promptly. However, if your next dose is approaching, skip the missed dose and resume your regular schedule. Avoid doubling the dose.
Store in a cool and dry place, and keep the temperature below 30�C
You have been prescribed Premarin Vaginal Cream as a part of hormone replacement therapy to relieve symptoms of menopause. It can be applied to the external vaginal area, or inserted into the vagina using the applicator provided. It does not expose the rest of your body to the medicine thereby avoiding side effects that happen more often with pills. Do not have sex right after using Premarin Vaginal Cream as some of the medicine can be absorbed into your partner's skin. Inform your doctor if you experience any vaginal bleeding or spotting, abnormal vaginal discharge or vaginal discomfort while using this medicine. Do not use Premarin Vaginal Cream if you are pregnant or breastfeeding, over 35, smoke, or have a history of blood clots or heart diseases.
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