Tranexamic Acid + Vitamin B3 (Niacin) + Vitamin C (Ascorbic Acid) is a topical dermatological combination containing tranexamic acid, niacinamide (vitamin B3), and vitamin C (ascorbic acid). It is used to help manage hyperpigmentation, melasma, post-inflammatory pigmentation, and uneven skin tone. It is commonly available as serums and facial cleansers and is typically used as part of a daily skincare routine under a dermatologist's guidance.

Tranexamic Acid + Vitamin B3 (Niacin) + Vitamin C (Ascorbic Acid) combines tranexamic acid, niacinamide (vitamin B3), and vitamin C (ascorbic acid). It is used to help manage hyperpigmentation, including melasma, post-inflammatory hyperpigmentation, and uneven skin tone.

Tranexamic acid may help reduce pigmentation by affecting skin pathways involved in inflammation and UV-related stimulation of melanin production. These pathways can contribute to increased pigment formation in the skin. Niacinamide helps reduce the transfer of melanin to the outer layers of the skin. It also supports the skin barrier, which may improve skin tolerance and reduce dryness or irritation in some people. Vitamin C acts as an antioxidant. It helps reduce damage from sun exposure and environmental factors and may also help regulate melanin formation in the skin.

Because the ingredients in Tranexamic Acid + Vitamin B3 (Niacin) + Vitamin C (Ascorbic Acid) work at different steps in the process that causes dark spots, regular use can slowly lighten them and make the skin tone look more even. The results can differ depending on your skin type and what is causing the pigmentation. Tranexamic Acid + Vitamin B3 (Niacin) + Vitamin C (Ascorbic Acid) is used as part of a skincare routine under a dermatologist's guidance. Consistent use is usually required before visible improvement is seen.

Tranexamic Acid + Vitamin B3 (Niacin) + Vitamin C (Ascorbic Acid) may be indicated for:

Melasma & Hyperpigmentation

Helps reduce the appearance of persistent dark patches, including melasma, with regular use over time.

Post-Inflammatory Hyperpigmentation (PIH)

May reduce the dark marks or spots that remain after acne, minor injuries, or skin irritation.

Skin Brightening & Radiance

Can improve overall clarity and reduce dullness, leading to a fresher, more radiant look.

Uneven Skin Tone & Texture

May help smooth out irregular pigmentation, making skin appear more uniform and reducing the appearance of enlarged pores.

Tranexamic Acid + Vitamin B3 (Niacin) + Vitamin C (Ascorbic Acid) may provide the following benefits:

• May help reduce the appearance of dark spots, melasma, and post-acne marks over time.

• May help improve uneven skin tone with regular use.

• Helps target different steps involved in skin pigmentation, including melanin production and transfer.

• May help protect the skin from oxidative stress caused by sun exposure and pollution.

• May help support the skin barrier and improve overall skin tolerance.

• It is generally well-suited for long-term use as part of a dermatologist-guided skincare routine.

Results vary depending on skin type, severity of pigmentation, and consistency of use.

Tranexamic Acid + Vitamin B3 (Niacin) + Vitamin C (Ascorbic Acid) is generally well-tolerated, but localised skin reactions can occur.

Common side effects may include:

• Mild tingling or redness upon application

• Dryness or slight peeling

• Temporary itching

Uncommon side effects may include:

• Increased sensitivity to the sun

• Localised skin rash or irritation

Serious side effects (uncommon) may include:

• Signs of a severe allergic reaction (hives, swelling of the face or throat)

• Severe burning or persistent inflammation

Always consult your doctor or dermatologist if you experience persistent irritation or signs of an allergic response.

• Apply Tranexamic Acid + Vitamin B3 (Niacin) + Vitamin C (Ascorbic Acid) as a thin layer on clean, dry skin.

• Use only on the affected areas or as directed by your dermatologist.

• Apply once daily or as prescribed, preferably at night unless advised otherwise.

• Use a small amount and spread evenly; avoid excessive application.

• Wash your hands before and after application.

• Avoid contact with the eyes, lips, and inside of the nose. If accidental contact occurs, rinse with water.

• Do not apply to broken, irritated, or infected skin.

• Allow the product to fully absorb before applying other skincare products.

• Use sunscreen during the day, as the skin may be more sensitive to sunlight during treatment.

• Use regularly for best results, as improvement in pigmentation is gradual.

Tranexamic Acid + Vitamin B3 (Niacin) + Vitamin C (Ascorbic Acid) works through a combination of actions that target different steps involved in skin pigmentation.

Tranexamic acid helps reduce pigmentation by interfering with pathways involved in the activation of melanocytes, particularly those triggered by inflammation and UV exposure. This may help limit the formation of excess melanin.

Niacinamide (vitamin B3) supports the skin barrier and helps reduce the transfer of melanin from deeper skin layers to the outer surface. This may gradually reduce the appearance of dark spots and uneven tone.

Vitamin C (ascorbic acid) acts as an antioxidant and helps reduce oxidative stress in the skin. It also inhibits tyrosinase, an enzyme involved in melanin production.

Together, these actions may help reduce existing hyperpigmentation and support a more even skin tone over time with consistent use.

• Perform a patch test on a small area of skin (such as the inner arm) before first use to check for irritation or sensitivity.

• Apply to clean, dry skin as part of your skincare routine.

• If you have sensitive skin, you may apply a moisturiser before and/or after the product to reduce irritation.

• Do not apply to broken, inflamed, or infected skin.

• Use a broad-spectrum sunscreen (SPF 30 or higher) daily.

• Avoid combining with other strong exfoliating or irritating skincare products.

• Use consistently as directed, as visible improvement in pigmentation typically takes time.

• Store Tranexamic Acid + Vitamin B3 (Niacin) + Vitamin C (Ascorbic Acid) at room temperature in a cool, dry place.

• Keep Tranexamic Acid + Vitamin B3 (Niacin) + Vitamin C (Ascorbic Acid) tightly closed and away from direct sunlight, as Vitamin C can oxidise and lose its potency.

• Keep out of reach of children and pets.

• General Diet (NO INTERACTION): Since this medicine is applied topically to the skin, food intake does not affect its absorption or effectiveness.

• Spicy Food (CAUTION): While not a direct interaction, spicy foods may sometimes worsen skin redness or flushing in sensitive individuals (e.g., rosacea). Patients with pigmentation concerns are advised to maintain a balanced diet and avoid triggers that aggravate skin sensitivity.

• Retinoids (CAUTION): Using Tranexamic Acid + Vitamin B3 (Niacin) + Vitamin C (Ascorbic Acid) alongside high‑strength retinoids may increase skin sensitivity. It is advisable to space out applications (e.g., retinoid at night, Tranexamic Acid + Vitamin B3 (Niacin) + Vitamin C (Ascorbic Acid) in the morning).

• Strong Acids (MODERATE): Combining Tranexamic Acid + Vitamin B3 (Niacin) + Vitamin C (Ascorbic Acid) with other acidic treatments (such as glycolic acid, salicylic acid, or lactic acid) may cause excessive peeling, redness, or irritation.

• Eczema / Rosacea (CAUTION): Vitamin C may cause stinging or irritation in individuals with sensitive or compromised skin barriers.

• Active Skin Infections (SEVERE): Do not apply to areas with active bacterial or fungal infections, as this may worsen irritation or delay healing.

Overdose is unlikely with topical use when applied as directed. However, excessive or frequent application over large areas of skin may increase the risk of irritation.

This may lead to symptoms such as redness, dryness, burning sensation, or peeling of the skin. In some cases, worsening of skin sensitivity may also occur. If irritation persists or becomes severe, stop using the product and seek medical advice.

If you miss an application, apply it as soon as you remember. If it is almost time for your next scheduled application, skip the missed one. Do not apply a double amount to make up for the missed dose.