Leucorin Tablet is used to prevent the harmful effects of methotrexate (anticancer medicine). It is also used in the treatment of methotrexate overdose. Leucorin Tablet can be taken with or without food. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It is generally safe medicine to use with no common side effects if taken in the right amount. Your doctor may request regular blood tests to monitor your blood cells and serum methotrexate concentration in the blood. Before taking it, tell your doctor if have seizures, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using, especially phenytoin for your seizures.
Written by: Syeda Jigni Mehraj, B pharmacy
Reviewed by: Dr. Jay Faldu, MBBS
Last updated on: 22-04-2025
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Leucorin Tablet is used to prevent the harmful effects of methotrexate (anticancer medicine). It is also used in the treatment of methotrexate overdose. Leucorin Tablet can be taken with or without food. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It is generally safe medicine to use with no common side effects if taken in the right amount. Your doctor may request regular blood tests to monitor your blood cells and serum methotrexate concentration in the blood. Before taking it, tell your doctor if have seizures, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using, especially phenytoin for your seizures.
Prevention of Harmful effects of methotrexate
In Prevention of Harmful effects of methotrexate Leucorin Tablet helps protect the body cells against the harmful effects of methotrexate, an anti-cancer medicine. It is a form of vitamin B that is given after 24 hours of methotrexate administration. This makes sure that methotrexate has achieved its anti-cancer effects and also, Leucorin Tablet will prevent the other side effects such as anemia.
The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you're worried about them.
Follow your doctor's guidance regarding the dose and duration of this medication. Ingest it without breaking or crushing. Do not chew, crush or break it. Leucorin Tablet can be taken it with or without food, although it's advisable to take it consistently at the same time.
Leucorin Tablet is a form of vitamin B. It works by protecting healthy cells from the toxic effects of methotrexate (anticancer medicine) while allowing it to enter and kill the cancer cells.
Alcohol
Consult your Doctor: Please consult your doctor regarding the safety of consuming alcohol with Leucorin Tablet . Experts have not found evidence of alcohol impairing the effectiveness of the medicine.
Pregnancy
Seek medical advice from your doctor: Leucorin Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Doctor consultation is advised.
Breast feeding
Seek medical advice from your doctor: Information regarding the use of Leucorin Tablet during breastfeeding is not available. Doctor consultation is advised.
Driving
SAFE - Leucorin Tablet does not usually affect your ability to drive.
Kidney
Seek medical advice from your doctor: There is limited information available on the use of Leucorin Tablet in patients with kidney disease. Doctor consultation is advised.
Liver
Seek medical advice from your doctor: There is limited information available on the use of Leucorin Tablet in patients with liver disease. Doctor consultation is advised.
If a dose of Leucorin Tablet is missed, take it promptly. However, if your next dose is approaching, skip the missed dose and resume your regular schedule. Avoid doubling the dose.
Store in a cool and dry place, and keep the temperature below 30�C
You have been prescribed Leucorin Tablet to reduce the side effects of the medicine methotrexate. Take it 24 hours after taking methotrexate. If taken at the same time, it may counteract the effect of methotrexate. Inform your doctor if you are also taking certain medications such as phenytoin for your seizures as Leucorin Tablet may counteract the antiepileptic effects.
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