Oxerute Cream 50gm is a medicine used to relieve symptoms of haemorrhoids, anal fissures, and other inflammatory conditions affecting the anal area. It combines several agents with different roles. Hydrocortisone helps reduce swelling and irritation. Lidocaine numbs the tissues to provide temporary pain relief. Phenylephrine narrows blood vessels, which may lessen bleeding and congestion. Zinc protects the skin and supports healing. Calcium Dobesilate and Troxerutin strengthen blood vessels and improve circulation. This medicine is available in topical creams, ointments, rectal gels, and suppositories. It is applied locally to ease discomfort such as pain, itching, swelling, and bleeding.
Written by: Syed Jommy Abbas, B. Pharma
Reviewed by: Dr. Devika Rani, MBBS
Last updated on: 13-05-2026
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Oxerute Cream 50gm is a medicine used to relieve symptoms of haemorrhoids, anal fissures, and other inflammatory conditions affecting the anal area. It combines several agents with different roles. Hydrocortisone helps reduce swelling and irritation. Lidocaine numbs the tissues to provide temporary pain relief. Phenylephrine narrows blood vessels, which may lessen bleeding and congestion. Zinc protects the skin and supports healing. Calcium Dobesilate and Troxerutin strengthen blood vessels and improve circulation. This medicine is available in topical creams, ointments, rectal gels, and suppositories. It is applied locally to ease discomfort such as pain, itching, swelling, and bleeding.
Oxerute Cream 50gm is a combination medicine used for the local treatment management of haemorrhoids, anal fissures, and other inflammatory anorectal conditions. It is available in topical creams, ointments, rectal gels, and suppositories, all designed to act directly at the site of discomfort. The formulation brings together anti‑inflammatory, anaesthetic, vasoprotective, and protective agents to relieve pain, itching, swelling, and bleeding.
Hydrocortisone is a corticosteroid that helps reduce inflammation and irritation. Lidocaine provides temporary pain relief by numbing the affected area. Phenylephrine acts as a decongestant by constricting blood vessels, which may lessen swelling and bleeding. Zinc serves as a skin protectant, supporting healing and reducing local irritation. Calcium Dobesilate and Troxerutin are vasoprotective agents that help strengthen blood vessels and improve circulation, which may reduce vascular fragility and leakage.
This medicine is usually prescribed for short courses under medical supervision. It may help ease discomfort and improve the quality of life in patients with haemorrhoids or related conditions. However, prolonged or inappropriate use, especially of corticosteroids and local anaesthetics, can increase the risk of side effects such as local irritation, allergic reactions, or worsening of symptoms.
Overall, Oxerute Cream 50gm is intended to provide symptomatic relief and support recovery in anorectal conditions. Safe and effective use depends on following medical advice, applying the medicine as directed, and limiting treatment to the recommended duration.
Oxerute Cream 50gm may be indicated by your doctor for:
Relief of pain, swelling, and bleeding associated with piles.
To soothe pain and promote the healing of small tears in the lining of the anus.
Management of inflammation of the rectal lining.
Relief of intense itching in the perianal area.
To assist in recovery and pain management after haemorrhoid surgery.
Oxerute Cream 50gm may provide benefits such as:
Oxerute Cream 50gm is generally safe for short-term localised use, but some side effects may occur.
Follow medical advice: Use Oxerute Cream 50gm exactly as prescribed. Do not continue treatment for longer than 7 days unless advised by a doctor.
Preparation: Gently clean the affected area with mild soap and warm water, then pat dry before application.
Topical cream/ointment: Apply a small amount to the external area 2–4 times daily, especially after bowel movements.
Internal use (rectal applicator): Attach the applicator to the tube, insert it gently into the rectum, and squeeze out the medicine. Clean the applicator thoroughly after each use.
Suppositories: Remove the foil wrapper, lie on your side, and insert the suppository pointed‑end first into the rectum. Remain lying down for a few minutes to allow it to melt and begin working.
Hygiene: Wash your hands before and after each application to prevent infection and ensure proper use.
Oxerute Cream 50gm acts locally in the anorectal area to ease discomfort from haemorrhoids, fissures, and related conditions. It combines several agents that work in different ways to reduce inflammation, relieve pain, control bleeding, and support healing.
Store Oxerute Cream 50gm at room temperature (20°C–25°C / 68°F–77°F) in a dry place.
Overdose is unlikely with topical use. However, if the medicine is swallowed or applied excessively over long periods, it can lead to lidocaine or steroid toxicity. If swallowed, seek emergency medical care immediately.
Apply the dose as soon as you remember. If it is almost time for your next dose, skip the missed one. Do not apply a double dose.
Therapeutic Class
Anti-hemorrhoidal
Action Class
Anorectal Anti-inflammatory / Analgesic
Chemical Class
Multi-class (Steroid, Anaesthetic, Vasoconstrictor, Protectant, Flavonoid)
Habit Forming
No
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