Preghype Plus Tablet SR is a combination medicine used for the treatment of neuropathic pain. This medicine decreases pain by controlling calcium channel activity of the nerve cells and increases the level of chemical messengers in the brain that help in regulating mood and protect nerve fibers.Preghype Plus Tablet SR can be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by the doctor. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine without talking to the doctor as it may worsen your symptoms.Some common side effects of this medicine include constipation, difficulty in urination, blurred vision and dryness of mouth. It may cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain and to control it, you should have a balanced diet and exercise regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts.Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Last updated on: 24-06-2025
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Preghype Plus Tablet SR is a combination medicine used for the treatment of neuropathic pain. This medicine decreases pain by controlling calcium channel activity of the nerve cells and increases the level of chemical messengers in the brain that help in regulating mood and protect nerve fibers.Preghype Plus Tablet SR can be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by the doctor. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine without talking to the doctor as it may worsen your symptoms.Some common side effects of this medicine include constipation, difficulty in urination, blurred vision and dryness of mouth. It may cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain and to control it, you should have a balanced diet and exercise regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts.Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Neuropathic pain
In Neuropathic pain : Preghype Plus Tablet SR is a combination of medicines used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles or spinal cord injury. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. Pregabalin, an active ingredient of this medicine, is thought to work by interfering with pain signals that travel through the damaged nerves and the brain. It also contains nutritional supplements that improve nerve conduction.Taking this medicine regularly will improve your physical and social functioning and overall quality of life. It takes a few weeks to work so you need to take it regularly even if you feel it is not doing any good. Once your symptoms have gone you should still keep taking the medicine until your doctor advises you to stop.
Side effects of Preghype Plus Tablet SRThe majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you�re worried about them Common side effects of Preghype Plus Constipation Difficulty in urination Weight gain Sleepiness Dizziness Tiredness Blurred vision Dryness in mouth Increased heart rate Orthostatic hypotension (sudden lowering of blood pressure on standing)Uncoordinated body movements
How to use Preghype Plus Tablet SRFollow your doctor's guidance regarding the dose and duration of this medication. Ingest it without breaking or crushing. Do not chew, crush or break it. Preghype Plus Tablet SR can be taken it with or without food, although it's advisable to take it consistently at the same time.
How Preghype Plus Tablet SR works Preghype Plus Tablet SR is a combination of four medicines: Pregabalin, Nortriptyline, Methylcobalamin and Vitamin D3. Pregabalin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells. Nortriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Methylcobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Vitamin D3 helps transmit messages from nerve cells to other cells in the body. Together, they relieve neuropathic pain (pain from damaged nerves).
Alcohol
Not Safe: Consuming alcohol with Preghype Plus Tablet SR may lead to excessive drowsiness.
Pregnancy
Preghype Plus Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Doctor consultation is advised.
Breast feeding
Preghype Plus Tablet SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
Preghype Plus Tablet SR may cause side effects which could affect your ability to drive.As Preghype Plus Tablet SR may affect your alertness which may affect your ability to drive.
Kidney
Preghype Plus Tablet SR is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Preghype Plus Tablet SR may not be needed in these patients. Doctor consultation is advised.
Liver
Preghype Plus Tablet SR is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Preghype Plus Tablet SR may not be needed in these patients. Please consult your doctor.
If a dose of Preghype Plus Tablet SR is missed, take it promptly. However, if your next dose is approaching, skip the missed dose and resume your regular schedule. Avoid doubling the dose.
Store in a cool and dry place, and keep the temperature below 30�C
Preghype Plus Tablet SR is used to treat certain types of long-lasting pain caused by damage to nerves. Inform your doctor if you are taking any other pain relieving medicines. Inform your doctor if you have a history of seizures. Immediately seek medical help if you experience hallucinations, fever, sweating, shivering, fast heart rate, muscle twitching, or loss of coordination. Along with taking Preghype Plus Tablet SR, your doctor might advise you to undergo physiotherapy to get relief rom pain.
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